Variations within the Glycan Shield of SARS-CoV-2 Impact Viral Spike DynamicsArticle Published on 2023-02-282023-07-11 Journal: Journal of Molecular Biology [Category] COVID19(2023년), [키워드] glycosylation mass spectrometry molecular dynamics SARS-CoV-2 Variant of concern. [DOI] 10.1016/j.jmb.2022.167928 PMC 바로가기
The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccineesArticle Published on 2023-01-012023-07-11 Journal: EBioMedicine [Category] COVID19(2023년), [키워드] antibodies COVID-19 fucosylation glycosylation mRNA vaccine. [DOI] 10.1016/j.ebiom.2022.104408 PMC 바로가기
Glycosylation in SARS-CoV-2 variants: A path to infection and recoveryReview Published on 2022-12-012023-07-10 Journal: Biochemical pharmacology [Category] COVID19(2023년), [키워드] glycobiology glycosylation Immunity Vaccine development. [DOI] 10.1016/j.bcp.2022.115335 PMC 바로가기 [Article Type] Review
[Research Progress in the Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Drugs Targeting Spike Protein]Article Published on 2022-12-012023-07-10 Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae [Category] COVID19(2023년), [키워드] Chinese medicine glycosylation inhibitor severe acute respiratory syndrome coronavirus 2 spike protein. [DOI] 10.3881/j.issn.1000-503X.15002 PMC 바로가기
Characterization and immunogenicity of SARS-CoV-2 spike proteins with varied glycosylationArticle Published on 2022-11-082022-11-15 Journal: Vaccine [Category] SARS, 진단, [키워드] 293 cells 293F cell acute respiratory syndrome addition binding caused Cell changed characterization convalescent sera coronavirus Coronavirus disease-19 COVID-19 Critical discrepancy effective Efficacy elicited exhibited expression globe glycosylated glycosylation glycosylation pattern homogeneity host cells IgG immunization immunogenicity insect cell mammalian cells mice Neutralizing antibody response neutralizing antibody titre pandemic Protein Proteins provide reactivity Receptor binding regimen robust S protein S-2P SARS-CoV-2 SARS-CoV-2 spike protein spike Spike. the S protein thermal stability Vaccine Vaccine design Variation virus virus entry while [DOI] 10.1016/j.vaccine.2022.09.057 PMC 바로가기
ACE2 N-glycosylation modulates interactions with SARS-CoV-2 spike protein in a site-specific mannerArticle Published on 2022-11-052022-11-16 Journal: Communications Biology [Category] SARS, 변종, [키워드] accumulated ACE2 ACE2 receptor binding binding site caused cellular changes in conserved Delta glycan glycosylation glycosylation deletion glycosylation site Guidance Interaction investigated lineages modulate mutated N-glycosylation omicron parental profile provide SARS-CoV-2 SARS-CoV-2 spike protein soluble ACE2 spike spike mutation the SARS-CoV-2 therapeutic use variant variants of concern virus VOCs [DOI] 10.1038/s42003-022-04170-6 PMC 바로가기
Identification of serum glycobiomarkers for Hepatocellular Carcinoma using lectin microarraysArticle Published on 2022-10-202023-06-13 Journal: Frontiers in Immunology [Category] B형 간염, Fulltext, [키워드] Biomarker glycosylation Hepatocellular carcinoma Immunoglobulin G immunoglobulin M lectin microarray. [DOI] 10.3389/fimmu.2022.973993 PMC 바로가기
Afucosylated IgG responses in humans – structural clues to the regulation of humoral immunityArticle Published on 2022-10-012022-11-15 Journal: Trends in immunology [Category] 진단, [키워드] adaptive complement conserved COVID-19 disease domain ENhance erythrocytes exacerbate excessive inflammation expressed Fc-receptors fucosylation Galactosylation glycosylation Health HIV-1 Human Humoral immunity humoral immunity. IgG IgG antibodies IgG response immune response Immunoglobulin implication Infectious disease Interaction malaria plasma IgG Plasmodium falciparum protective immunity Protein raised recent Regulation Regulatory response responses vaccination virus [DOI] 10.1016/j.it.2022.08.001 PMC 바로가기
Serum N-glycomic profiling may provide potential signatures for surveillance of COVID-19Article Published on 2022-09-192022-11-16 Journal: Glycobiology [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome alterations Analysis caused change changes in Clustering analysis Cohort cohorts contrary coronavirus COVID-19 COVID-19 infection described disease Features glycan glycoprotein glycosylation Health healthy control healthy controls heatmap help Hierarchical identify InstantPC pandemic performed platform positive profile progression Protein protein glycosylation SARS-CoV-2 SARS-COV-2 infection serum serum glycomics. significantly higher similarity Surveillance Symptoms the disease traits Variability variable virus [DOI] 10.1093/glycob/cwac051 PMC 바로가기
Evidence for Different Virulence Determinants and Host Response after Infection of Turkeys and Chickens with Highly Pathogenic H7N1 Avian Influenza VirusArticle Published on 2022-09-142023-06-22 Journal: Journal of Virology [Category] 조류인플루엔자, [키워드] Avian influenza virus chickens cleavage site glycosylation H7N1 high pathogenicity host response Transcriptome Turkeys virulence determinants. [DOI] 10.1128/jvi.00994-22 PMC 바로가기